Maps & Directions

Hospital Services

At Portsmouth Regional Hospital, we treat the most important health concerns - yours. We provide healthcare services designed to meet your needs at every stage of your life.

Find a Doctor

We value the knowledgeable and experienced physicians affiliated with our hospital, and collaborate closely with them to continuously delivery quality patient care.

Patients & Visitors

Patient care is our most important job. We want to make sure your experience is as pleasant as possible. This section contains information to help make your stay with us as comfortable as possible.

Career Center

Do you share our passion for delivering high quality and safe patient care? If so, check out positions where you can further your career and enjoy a healthy work/life balance.

About PRH

At Portsmouth Regional Hospital, our focus is simple - putting Patients First. We have embraced this philosophy by focusing on patient care practices and new technology, keeping patient safety a top priority. At Portsmouth Regional Hospital, you’re going to be treated as an individual, with compassion and care, like one of the family. Our Patients First approach is clear...excellent service, every patient, every time.

Health Library

The more you know about your health, the better prepared you are to make informed healthcare decisions. Our health library gives you the information you need to take charge of your health.

For Clinicians

This section is specifically for healthcare professionals, including physicians, mid-level providers, nurses, and other medical professionals.

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Maps & Directions

Campus Map and Directory

Portsmouth Regional Hospital - First Floor - Floor Plan

Driving Directions

Portsmouth Regional Hospital is easily accessible by major highways in New Hampshire, Maine and Massachusetts. This website contains street maps for all the physicians on our active medical staff. To find out where your doctor is located, please visit the Doctors section of our website.

To Portsmouth Regional Hospital

Traveling north:

Take I-95 North to Exit 3, the first Portsmouth exit. Turn right onto Route 33 eastbound. Proceed about 600 feet to the traffic light and make a left turn. The road veers to the right and becomes Borthwick Avenue. Follow Borthwick Avenue to Portsmouth Regional Hospital on the left.

Traveling south:

Take I-95 South to Exit 3B Greenland and then left at the Exit to Route 33. Turn right onto Route 33 eastbound. Cross over I-95 and proceed about 600 feet to the traffic light and make a left turn. The road veers to the right and becomes Borthwick Avenue. Follow Borthwick Avenue to Portsmouth Regional Hospital on the left.

Traveling east on Routes 4 and 16:

US-4 E becomes NH-16 S. Enter the Portsmouth Traffic Circle, travel half-way around the circle and follow signs for Route 1 By-pass South. Take a right onto Borthwick Avenue. Portsmouth Regional Hospital is on the right.

To Lafayette Professional Park

Traveling north:

Take I-95 North to Exit 3, the first Portsmouth exit. Turn right onto Route 33 eastbound, proceeding east for about 1.5 miles. Make a right onto South Street. Follow South Street to Lafayette Professional Park on your right at the intersection of South Street and Route 1 (Lafayette Road).

Traveling south:

Take I-95 South to Exit 5 in Portsmouth. Take an immediate right, following the signs for the Route 1 By-Pass into the Portsmouth Traffic Circle. Follow the Route 1-Bypass south for 1 mile and turn left onto Greenleaf Avenue. Proceed north on Greenleaf Ave. until it merges onto Route 1 North. Turn left onto South Street. Lafayette Professional Park is on your left at the intersection of South Street and Route 1 (Lafayette Road).