von Willebrand Disease
- Type 1—most mild and most common form
- Type 2
- Type 3—most serious form and very rare
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- Type 1—results in low levels of von Willebrand factor
- Type 2—results in von Willebrand factor that does not work well
- Type 3—results in no von Willebrand factor
- Easy bruising
- Frequent or prolonged nosebleeds
- Prolonged bleeding from the gums and minor cuts
- Heavy or prolonged bleeding during menstrual periods
- Bloody urine
- Prolonged bleeding after injury, childbirth, surgery, or invasive dental procedures
- Desmopressin (nasal spray or injection)—raises the level of vWF in the blood. May be used to control bleeding in mild cases of type 1.
- Intravenous infusions of von Willebrand factors—to control your bleeding.
- Birth control pills—to control heavy menstrual periods in women with type 1 vWD.
- Antifibrinolytic medicine—for bleeding in the nose or mouth. Keeps a clot from being dissolved before the bleeding has stopped.
- Recombinant Factor VIIIa—if a antibodies to von Willebrand Factor are developed.
National Heart, Lung, and Blood Institute http://www.nhlbi.nih.gov
National Hemophilia Foundation http://www.hemophilia.org
Health Canada http://www.hc-sc.gc.ca/
Network of Rare Blood Disorders Organizations http://www.hemophilia.ca/
von Willebrand disease. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php . Updated June 29, 2011. Accessed December 27, 2012.
von Willebrand disease. National Hemophilia Foundation website. Available at: http://www.hemophilia.org/bdi/bdi%5Ftypes3.htm . Accessed December 27, 2012.
von Willebrand disease. National Heart Lung and Blood Institute website. Available at: http://www.nhlbi.nih.gov/health/health-topics/topics/vwd/ . Accessed December 27, 2012.
von Willebrand’s disease: what you need to know about this inherited disorder. Am J Nurs . February 2000.
- Reviewer: Michael Woods, MD
- Review Date: 11/2012 -
- Update Date: 11/26/2012 -