Immune Thrombocytopenia Purpura
(Idiopathic Thrombocytopenic Purpura; ITP)
- Lasts less than six months.
- Usually occurs in children.
- Most common type of ITP.
- Lasts longer than six months.
- Usually occurs in adults.
|Copyright © Nucleus Medical Media, Inc.|
- Children with a recent viral infection or live virus vaccination
- Women—2-3 times more likely to get ITP than in men
- Women younger than 40
- Easy bruising
- Blood in urine or stools
- Bleeding for longer than normal following an injury
- Unexplained nosebleeds
- Bleeding from the gums
- In adult women, heavier-than-normal menstrual periods
- Red dots—may occur in groups and resemble a rash
- Bleeding within the intestinal tract or brain (rare)
- Test your blood's clotting ability
- Analyze levels of different blood cells including platelets
- Look for infections or other medical issues associated with ITP
- Eliminate other medical conditions
- Steroids—to lowers the activity of the immune system. This will decrease the destruction of platelets.
- Gamma globulin infusions—also slows down platelet destruction. An infusion means that it is given by IV or through a shot. It usually works more quickly than steroids.
- Eltrombopag (Promacta)
- Romiplostim (Nplate)
- Take precautions in your child's environment. Consider padding an infant's crib or play area.
- Make sure that older children wear helmets and protective gear when playing sports. This will help to reduce bruising injuries.
- Consider temporarily stopping contact sports such as football and even rougher game playing when platelet counts are low.
- Avoid medications that contain aspirin or ibuprofen . These medicines can reduce platelet activity.
- Eat a healthful diet . It should be low in saturated fat and rich in whole grains, fruits, and vegetables.
- Get regular exercise .
- If you are overweight, lose weight .
- Don’t smoke. If you smoke, quit .
- Drink alcohol only in moderation. Moderate alcohol intake is two drinks per day for men and one drink per day for women.
American Academy of Family Physicians http://www.familydoctor.org/
National Heart, Lung, and Blood Institute http://www.nhlbi.nih.gov/
National Institute of Diabetes and Digestive and Kidney Diseases http://www2.niddk.nih.gov/
Canadian Medical Association Journal http://www.cmaj.ca/
Health Canada http://www.hc-sc.gc.ca/
Bussel JB; Cheng G; Saleh MN; Psaila B; Kovaleva L; Meddeb B; Kloczko J; Hassani H; Mayer B; Stone NL; Arning M; Provan D; Jenkins JM. Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura. N Engl J Med . 2007 Nov 29;357(22):2237-47.
Immune thrombocytopenia (ITP). EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php . Updated May 4, 2012. Accessed September 27, 2012.
George JN, Woolf SH, Raskob GE, et al. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for The American Society of Hematology. American Society of Hematology website. Available at: http://www.hematology.org/practice/idiopathic.cfm . Accessed Dec 12, 2006.
Karpatkin S. Autoimmune (idiopathic) thrombocytopenic purpura. Lancet . 1997;349:1531-1536.
Newland A; Caulier MT; Kappers-Klunne M; Schipperus MR; Lefrere F; Zwaginga JJ; Christal J; Chen CF; Nichol JL. An open-label, unit dose-finding study of AMG 531, a novel thrombopoiesis-stimulating peptibody, in patients with immune thrombocytopenic purpura. Br J Haematol . 2006 Nov;135(4):547-53.
What is immune thrombocytopenia? National Heart Lung and Blood Institute website. Available at: http://www.nhlbi.nih.gov/health/health-topics/topics/itp/ . Updated March 14, 2012. Accessed September 27, 2012.
- Reviewer: Michael Woods, MD
- Review Date: 09/2012 -
- Update Date: 00/93/2012 -